Neuro Service Line
Explore AI apps curated for multiple Neurological pathologies/conditions on Calantic platform, featuring Ischemic Stroke and Neurodegenerative disease.
Ischemic Stroke & ICH Triage
CINA is a radiological computer aided triage and notification software indicated for use in the analysis of non-enhanced head CT (NCCT) images and CT angiography (CTA) of the head.
The device is intended to assist hospital networks and trained radiologists in workflow triage by flagging and communicating suspected positive findings of head NCCT images for Intracranial Hemorrhage (ICH) and head CTA for large vessel occlusion (LVO) of the anterior circulation (distal ICA, MCA-M1 or proximal MCA-M2)1.
Non-Contrast CT
CT Angiography
Ischemic Stroke ASPECTS
CINA-ASPECTS is a computer-aided diagnosis software device used to assist clinicians, including stroke physicians and radiologists, in the assessment and characterization of brain tissue abnormalities using CT image data. The Software automatically reorients images, segments and analyzes ASPECTS Regions of Interest (ROIs). The software extracts image data for the ROI(s) to provide analysis and computer analytics based on morphological characteristics2.
Non-Contrast CT
Ischemic Stroke Assessment
e-CTA* is a software medical device for processing brain CT Angiography (CTA) scans for stroke patients. e-CTA is indicated as an aid to diagnosis and treatment of acute ischemic stroke patients with carotid or Middle Cerebral Artery (MCA) - M1 and proximal M2 occlusion. The analysis capabilities are for detection and changes in the image related to acute stroke, including assessment of collateral status, and visualization of these changes3.
CT Angiography
Ischemic stroke ASPECTS & ICH Assessment
e-ASPECTS* is software medical device that provides both analysis and viewing capabilities for brain CT datasets of stroke patients. The analysis capabilities are for detection of changes in the imaged related to stroke, calculation of the extent of these changes (as ASPECTS) and visualization of these changes. e-ASPECTS is indicated as an aid to diagnosis and treatment of acute ischemic stroke patients with a Middle Cerebral Artery (MCA) occlusion. e-ASPECT also highlight suspected abnromal hyperdensities4.
Non-Contrast CT
Ischemic Stroke CT Perfusion
e-CTP* is a software medical device for processing brain CT Perfusion (CTP) scans. e-CTP provides both analysis and viewing capabilities for brain CT Perfusion datasets. The analysis capabilities are for characterization of perfusion parameters in the image following the injection of a contrast bolus, and visualization of these parameters. The parameters measured include relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), Tmax, Time to peak (TTP) and Mean transit time (MTT)5.
CT Perfusion
Neurodegenerative Diseases Volumetry Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated volumetric data, in addition to the image data at hand, can assist radiologists in detecting neurological diseases6.
MRI
Multiple Sclerosis White matter lesion Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated data, in addition to the image data at hand, can assist radiologists in diagnosis and monitoring of patients with Multiple Sclerosis and Vascular Dementia according to MAGNIMS criteria6.
MRI
Aneurysm Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated data, in addition to the image data at hand, can assist radiologists in diagnosis and monitoring of untreated intracranial (saccular) aneurysms6.
MRI
Neurodegenerative Disease Volumetry assessment
Icobrain ct and icobrain mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of CT or MR images.
icobrain ct provides normalized volume of the whole brain and normalized volume of lateral ventricules.
Icobrain mr provides normalized volume and volume changes of the hippocampi, cortex (frontal, temporal and parietal), whole brain, lateral ventricles and their ratio. It also includes unnormalized volume and volume changes of FLAIR white matter hyperintensities7,8.
Non- contrast CT
MRI
Multiple Sclerosis Lesion assessment
icobrain mr is intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of MR images. It provides unnormalized volume and volume changes of FLAIR white matter hyperintensities and T1 white matter hyperintensities and hypointensities. It also provides normalized volume and volume changes of the whole brain and gray matter8.
MRI
Traumatic Brain Injury Assessment
Icobrain ct and icobrain mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of CT or MR images. icobrain ct provides unnormalized measurement of the midline shift and volumes of NCCT hyperdensities. It includes normalized volume of basal cisterns along with left, right and fourth ventricule. icobrain mr provides unnormalized volume and volume changes of FLAIR white matter hyperintensities and includes normalized volume and volume changes of the cortical gray matter and hippocampi7,8.
Non-Contrast CT
MRI
Dynamic Susceptibility Contrast (DSC) images
The IB Neuro module, part of IB Clinic, performs post-processing of dynamically acquired CT and MR datasets to evaluate image intensity variations over time. The software generates dynamic susceptibility contrast (DSC) parametric images. These include relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), time to peak (TTP), and mean transit time (MTT)9.
MRI
Delta T1 maps
The IB Delta Suite module, part of IB Clinic, performs post-processing of DICOM images and simplifies post-processing tasks. It includes automated image registration features requiring minimal user interaction. It performs Voxel Intensity Calibration™ (“standardization”) of MR images. The software allows for the creation of different images to ease identification of changes between two images (e.g., signal changes due to contrast uptake between pre- and postcontrast images)9.
MRI
Dynamic contrast enhancement (DCE) images
The IB DCE module, part of IB Clinic, performs post-processing of dynamically acquired MR datasets to evaluate image intensity variations over time. The software generates dynamic contrast enhancement (DCE) parametric images. These include the Ktrans transfer constant, extravascular, extracellular fractions (ve), and blood plasma fraction (vp)9.
MRI
Dynamic Diffusion Analysis
The IB Diffusion module, part of IB Clinic, performs post-processing of MR diffusionweighted images (DWI) to determine diffusion-related parameters. The software generates parametric images such as apparent diffusion coefficient (ADC)9.
MRI
Ischemic Stroke & ICH Triage
CINA is a radiological computer aided triage and notification software indicated for use in the analysis of non-enhanced head CT (NCCT) images and CT angiography (CTA) of the head.
QThe device is intended to assist hospital networks and trained radiologists in workflow triage by flagging and communicating suspected positive findings of head NCCT images for Intracranial Hemorrhage (ICH) and head CTA for large vessel occlusion (LVO) of the anterior circulation (distal ICA, MCA-M1 or proximal MCA-M2)1.
CINA has CE marking and risk class I.
Non-Contrast CT
CT Angiography
Ischemic Stroke ASPECTS
CINA-ASPECTS is a computer-aided diagnosis software device used to assist clinicians, including stroke physicians and radiologists, in the assessment and characterization of brain tissue abnormalities using CT image data. The Software automatically reorients images, segments and analyzes ASPECTS Regions of Interest (ROIs). The software extracts image data for the ROI(s) to provide analysis and computer analytics based on morphological characteristics2.
CINA-ASPECTS has CE marking and risk class I
Non-Contrast CT
Ischemic Stroke Assessment
e-CTA* is a software medical device for processing brain CT Angiography (CTA) scans for stroke patients. e-CTA is indicated as an aid to diagnosis and treatment of acute ischemic stroke patients with carotid or Middle Cerebral Artery (MCA) - M1 and proximal M2 occlusion. The analysis capabilities are for detection and changes in the image related to acute stroke, including assessment of collateral status, and visualization of these changes3.
e-CTA has CE marking (CE0197) and risk class IIa
CT Angiography
Ischemic stroke ASPECTS & ICH Assessment
e-ASPECTS* is software medical device that provides both analysis and viewing capabilities for brain CT datasets of stroke patients. The analysis capabilities are for detection of changes in the imaged related to stroke, calculation of the extent of these changes (such as ASPECTS) and visualization of these changes. e- ASPECTS is indicated as an aid to diagnosis and treatment of acute ischemic stroke patients with a Middle Cerebral Artery (MCA) occlusion. e- ASPECT also highlight suspected abnromal hyperdensities4.
e-ASPECTS has CE marking (CE0197) and risk class IIa
Non-Contrast CT
Ischemic Stroke CT Perfusion
e-CTP* is a software medical device for processing brain CT Perfusion (CTP) scans. e-CTP provides both analysis and viewing capabilities for brain CT Perfusion datasets. The analysis capabilities are for characterization of perfusion parameters in the image following the injection of a contrast bolus, and visualization of these parameters. The parameters measured include relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), Tmax, Time to peak (TTP) and Mean transit time (MTT)5.
e-CTP has CE marking (CE0197) and risk class IIa
CT Perfusion
Neurodegenerative Diseases Volumetry Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated volumetric data, in addition to the image data at hand, can assist radiologists in detecting neurological diseases6.
mdbrain has CE marking (CE0123) and risk class IIb.
MRI
Multiple Sclerosis White matter lesion Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated data, in addition to the image data at hand, can assist radiologists in diagnosis and monitoring of patients with Multiple Sclerosis and Vascular Dementia according to MAGNIMS criteria6.
mdbrain has CE marking (CE0123) and risk class IIb.
MRI
Aneurysm Assessment
mdbrain is intended for automatic labeling, visualization, and volumetric quantification of 3D MRI data (in DICOM format) of the head. The software automates the currently manual process of identifying, labeling and volumetric calculation of segmented brain structures on 3D MRI images.
The calculated data, in addition to the image data at hand, can assist radiologists in diagnosis and monitoring of untreated intracranial (saccular) aneurysms6.
mdbrain has CE marking (CE0123) and risk class IIb.
MRI
Neurodegenerative Disease Volumetry assessment
Icobrain ct and icobrain mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of CT or MR images.
icobrain ct provides normalized volume of the whole brain and normalized volume of lateral ventricules.
Icobrain mr provides normalized volume and volume changes of the hippocampi, cortex (frontal, temporal and parietal), whole brain, lateral ventricles and their ratio. It also includes unnormalized volume and volume changes of FLAIR white matter hyperintensities7,8.
icobrain ct and icobrain mr have CE marking (CE1639) and risk class Im.
Non- contrast CT
MRI
Multiple Sclerosis Lesion assessment
icobrain mr iis intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of MR images. It provides unnormalized volume and volume changes of FLAIR white matter hyperintensities and T1 white matter hyperintensities and hypointensities. It also provides normalized volume and volume changes of the whole brain and gray matter8.
icobrain mr has CE marking (CE1639) and risk class Im.
MRI
Traumatic Brain Injury Assessment
Icobrain ct and icobrain mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of CT or MR images. icobrain ct provides unnormalized measurement of the midline shift and volumes of NCCT hyperdensities. It includes normalized volume of basal cisterns along with left, right and fourth ventricule. icobrain mr provides unnormalized volume and volume changes of FLAIR white matter hyperintensities and includes normalized volume and volume changes of the cortical gray matter and hippocampi7,8.
icobrain ct and icobrain mr have CE marking (CE1639) and risk class Im.
Non-Contrast CT
MRI
Dynamic Susceptibility Contrast (DSC) images
The IB Neuro module, part of IB Clinic, performs post-processing of dynamically acquired CT and MR datasets to evaluate image intensity variations over time. The software generates dynamic susceptibility contrast (DSC) parametric images. These include relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), time to peak (TTP), and mean transit time (MTT)9.
IB Clinic has CE marking and risk class I.
MRI
Delta T1 maps
The IB Delta Suite module, part of IB Clinic, performs post-processing of DICOM images and simplifies post-processing tasks. It includes automated image registration features requiring minimal user interaction. It performs Voxel Intensity Calibration™ (“standardization”) of MR images. The software allows for the creation of difference images to ease identification of changes between two images (e.g., signal changes due to contrast uptake between pre- and postcontrast images)9.
IB Clinic has CE marking and risk class I.
MRI
Dynamic contrast enhancement (DCE) images
The IB DCE module, part of IB Clinic, performs post-processing of dynamically acquired MR datasets to evaluate image intensity variations over time. The software generates dynamic contrast enhancement (DCE) parametric images. These include the Ktrans transfer constant, extravascular, extracellular fractions (ve), and blood plasma fraction (vp)9.
IB Clinic has CE marking and risk class I.
MRI
Dynamic Diffusion Analysis
The IB Diffusion module, part of IB Clinic, performs post-processing of MR diffusionweighted images (DWI) to determine diffusion-related parameters. The software generates parametric images such as apparent diffusion coefficient (ADC)9.
IB Clinic has CE marking and risk class I.
MRI
Ischemic Stroke & ICH
VENDOR
CINA (for ICH)
CINA (for LVO)
CINA-ASPECTS
DESCRIPTION
CINA is a computer-aided triage and notification software that assists in prioritizing worklists by flagging and communicating suspected positive findings of lntracranial Hemorrhage (ICH) and large vessel occlusion (LVO).1 3CINA-ASPECTS is a tool for assessing and characterizing brain tissue abnormalities in NCCT images in patients with known MCA or ICA occlusion, supporting the extent evaluation through ASPECT scores.2
MODALITY
CT
Traumatic Brain Injury
VENDOR
icobrain ct
icobrain mr
DESCRIPTION
icobrain ct and mr support the interpretation of standardized and quantified brain scans for traumatic brain injuries by uncovering mass effects and diffuse consequences of brain damage3,4
MODALITY
CT, MRI
Neurodegenerative Disease
VENDOR
icobrain ct
icobrain mr
DESCRIPTION
icobrain ct and mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of NCCT or MR images3,4
MODALITY
CT, MRI
Multiple Sclerosis
VENDOR
icobrain mr
DESCRIPTION
icobrain mr supports the assessment of brain lesion dissemination by detecting, quantifying, and tracking the evolution of FLAIR white matter hyperintensities, T1 white matter hypointensities and contrast-enhancing T1 hyperintensities to evaluate MS disease activity.4
MODALITY
MRI
Oncology
VENDOR
IB Clinic
DESCRIPTION
IB Clinic is designed to aid trained physicians in advanced image assessment, treatment consideration, and monitoring of therapeutic response. It generates various perfusion and diffusion related parameters, standardized image sets, and image intensity differences.5
MODALITY
MRI
Aneurysm
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in detecting and characterizing aneurysms**.6
**The algorithm currently only detects saccular aneurysms.
MODALITY
MRI
Neurodegenerative Disease
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in volumetric calculation of different brain volumes.6
MODALITY
MRI
Multiple Sclerosis
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in lesion detection and characterization according to MAGNIMS criteria.6
MODALITY
MRI
*Currently not available within the Calantic Viewer. Separately distributed by Bayer.
- CINA has CE marking and risk class I.
- CINA-ASPECTS has CE marking and risk class I
- e-CTA has CE marking (CE0197) and risk class IIa
- e-ASPECTS has CE marking (CE0197) and risk class IIa
- e-CTP has CE marking (CE0197) and risk class IIa
- mdbrain has CE marking (CE0123) and risk class IIb.
- icobrain ct and icobrain mr have CE marking (CE1639) and risk class Im.
- icobrain mr has CE marking (CE1639) and risk class Im.
- IB Clinic has CE marking and risk class I.
- Instructions for Use CINA, software version 1.0
- Instructions for Use CINA-ASPECTS, software version 1.4
- Instructions for Use e-CTA, software version 11.2
- Instructions for Use e-ASPECTS, software version 11.2
- Instructions for Use e-CTP, software version 11.2
- Instructions for Use mdbrain, software version 4.6
- Instructions for Use icobrain ct, software version 6.1
- Instructions for Use icobrain mr, software version 5.8
- Instructions for Use IB Clinic, software version 2.0
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Ischemic Stroke & ICH
VENDOR
CINA (for ICH)
CINA (for LVO)
CINA-ASPECTS
DESCRIPTION
CINA is a computer-aided triage and notification software that assists in prioritizing worklists by flagging and communicating suspected positive findings of lntracranial Hemorrhage (ICH) and large vessel occlusion (LVO).1 CINA-ASPECTS is a tool for assessing and characterizing brain tissue abnormalities in NCCT images in patients with known MCA or ICA occlusion, supporting the extent evaluation through ASPECT scores.2
MODALITY
CT
Traumatic Brain Injury
VENDOR
icobrain ct
icobrain mr
DESCRIPTION
icobrain ct and mr support the interpretation of standardized and quantified brain scans for traumatic brain injuries by uncovering mass effects and diffuse consequences of brain damage.3,4
MODALITY
CT, MRI
Neurodegenerative Disease
VENDOR
icobrain ct
icobrain mr
DESCRIPTION
icobrain ct and mr are intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of NCCT or MR images.3,4
MODALITY
CT, MRI
Multiple Sclerosis
VENDOR
icobrain mr
DESCRIPTION
icobrain mr supports the assessment of brain lesion dissemination by detecting, quantifying, and tracking the evolution of FLAIR white matter hyperintensities, T1 white matter hypointensities and contrast-enhancing T1 hyperintensities to evaluate MS disease activity.4
MODALITY
MRI
Oncology
VENDOR
IB Clinic
DESCRIPTION
IB Clinic is designed to aid trained physicians in advanced image assessment, treatment consideration, and monitoring of therapeutic response. It generates various perfusion and diffusion related parameters, standardized image sets, and image intensity differences.5
MODALITY
MRI
Aneurysm
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in detecting and characterizing aneurysms**.6
**The algorithm currently only detects saccular aneurysms.
MODALITY
MRI
Neurodegenerative Disease
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in volumetric calculation of different brain volumes.6
MODALITY
MRI
Multiple Sclerosis
VENDOR
mdbrain
DESCRIPTION
mdbrain is intended for automatic labeling, visualization and volumetric quantification of 3D MRI. The calculated data can assist radiologists in lesion detection and characterization according to MAGNIMS criteria.6
MODALITY
MRI
PATHOLOGY
Covid-19
Vendor
APP icolung ct
DESCRIPTION
icolung ct supports automatic labeling, visualization and volumetric quantification of segmentable lung structures from non-contrast enhanced chest CT. It also measures percentage of abnormality in each lobe and in total lungs.5
MODALITY
CT
Icolung ct has CE marking (CE1639) and risk class Im.
PATHOLOGY
COPD & ILD
Vendor
APP VIDA Insights
DESCRIPTION
VIDA Insights provides quantitative chest CT analysis used to profile and manage patients with/or at-risk of lung disease. It provides a flag of lung density abnormalities that may be indicative of emphysema (COPD) or interstitial lung abnormalities (ILAs).4
MODALITY
CT
VIDA Insights has CE marking (CE0413) and risk class IIa.
Not all offerings are available in all market. For availability specific to your country please contact your local Bayer representative.
Contraindications: HealthPNX+ device and HealthCXR device should not be used to analyze scans of patients under 18 years old, scans which are not AP or PA chest x-ray, scans with severe missing image artifacts, scans missing parts of the chest cavity or scans that are unnaturally monochrome in nature (too black or too white). Non-standard scans may skew analysis results, and if such scans are sent to the HealthPNX+device or HealthCXR device, physicians should disregard results from the scans. No other contraindications are described.
- Instructions for Use HealthPNX+ V2.0: Pneumothorax Triage Device, software version 2.0
- Instructions for Use HealthCXR Triage Device, software version 1.0
- Instructions for Use ClearRead CT, software version 3.6.0 - 5.5.0
- Instructions for Use icolung ct, software version 0.7.2